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Index > Protein center > Ifnar1(Gene name) > Mouse
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  • Ifnar1 (Gene name),
  • Interferon alpha/beta receptor 1 (Protein name ),  INAR1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ifnar1(Ifar;Ifnar);
    Protein name:
    Interferon alpha/beta receptor 1(IFN-R-1;IFN-alpha/beta receptor 1);
    Alternative:
    Type I interferon receptor 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterodimer with IFNAR2; in presence of interferon alpha and beta ligands, the heterodimer forms the type I interferon receptor. Interacts with STAT1 and STAT2. Interacts with IFNAR2.
    Function:
    Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    590
    Sequence:
    50:
    MLAVVGAAAL | VLVAGAPWVL | PSAAGGENLK | PPENIDVYII | DDNYTLKWSS | 
    100:
    HGESMGSVTF | SAEYRTKDEA | KWLKVPECQH | TTTTKCEFSL | LDTNVYIKTQ | 
    150:
    FRVRAEEGNS | TSSWNEVDPF | IPFYTAHMSP | PEVRLEAEDK | AILVHISPPG | 
    200:
    QDGNMWALEK | PSFSYTIRIW | QKSSSDKKTI | NSTYYVEKIP | ELLPETTYCL | 
    250:
    EVKAIHPSLK | KHSNYSTVQC | ISTTVANKMP | VPGNLQVDAQ | GKSYVLKWDY | 
    300:
    IASADVLFRA | QWLPGYSKSS | SGSRSDKWKP | IPTCANVQTT | HCVFSQDTVY | 
    350:
    TGTFFLHVQA | SEGNHTSFWS | EEKFIDSQKH | ILPPPPVITV | TAMSDTLLVY | 
    400:
    VNCQDSTCDG | LNYEIIFWEN | TSNTKISMEK | DGPEFTLKNL | QPLTVYCVQA | 
    450:
    RVLFRALLNK | TSNFSEKLCE | KTRPGSFSTI | WIITGLGVVF | FSVMVLYALR | 
    500:
    SVWKYLCHVC | FPPLKPPRSI | DEFFSEPPSK | NLVLLTAEEH | TERCFIIENT | 
    550:
    DTVAVEVKHA | PEEDLRKYSS | QTSQDSGNYS | NEEEESVGTE | SGQAVLSKAP | 
    590:
    CGGPCSVPSP | PGTLEDGTCF | LGNEKYLQSP | ALRTEPALLC | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse IFN-R-1
    Cat.:
    E1425h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse IFN-R-1
    Cat.:
    E1425b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse IFN-R-1
    Cat.:
    E1425m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse IFN-R-1
    Cat.:
    E1425p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse IFN-R-1
    Cat.:
    U1425m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse IFN-R-1
    Cat.:
    U1425h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse IFN-R-1
    Cat.:
    U1425b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse IFN-R-1
    Cat.:
    U1425p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse IFN-R-1
    Cat.:
    P1425Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse IFN-R-1
    Polyclonal Antibody for Mouse IFN-R-1
    Polyclonal Antibody for Mouse IFN-R-1
    Cat.:
    P1425Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse IFN-R-1
    Monoclonal Antibody for Mouse IFN-R-1
    Monoclonal Antibody for Mouse IFN-R-1
    Monoclonal Antibody for Mouse IFN-R-1
    Protein for Mouse IFN-R-1
    Protein for Mouse IFN-R-1
    Protein for Mouse IFN-R-1
    Protein for Mouse IFN-R-1

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    Linearity
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    References
    1. 1.
      "Behavior of a cloned murine interferon alpha/beta receptor expressed in homospecific or heterospecific background."
      Uze G. , Lutfalla G. , Bandu M.T. , Proudhon D. , Mogensen K.E.
      Proc. Natl. Acad. Sci. U.S.A.89:4774-4778(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Structure of the murine interferon alpha/beta receptor-encoding gene: high-frequency rearrangements in the interferon-resistant L1210 cell line."
      Lutfalla G. , Uze G.
      Gene148:343-346(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Hippocampus.
      tissue: Skin.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
      tissue: Eye.
    6. 6.
      "Trex1 prevents cell-intrinsic initiation of autoimmunity."
      Stetson D.B. , Ko J.S. , Heidmann T. , Medzhitov R.
      Cell134:587-598(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
    7. 7.
      "Structural basis of a unique interferon-beta signaling axis mediated via the receptor IFNAR1."
      de Weerd N.A. , Vivian J.P. , Nguyen T.K. , Mangan N.E. , Gould J.A. , Braniff S.J. , Zaker-Tabrizi L. , Fung K.Y. , Forster S.C. , Beddoe T. , Reid H.H. , Rossjohn J. , Hertzog P.J.
      Nat. Immunol.14:901-907(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 27-429 IN COMPLEX WITH IFNB1;DISULFIDE BONDS;FUNCTION;DISRUPTION PHENOTYPE
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